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Oral metoprolol tartrate therapy can be initiated after intravenous metoprolol tartrate therapy or, alternatively, oral treatment can begin within 3 to 10 days of the acute event see dosage and administration, contraindications, and warnings .
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The following side effects have been reported during post-approval use of toprol xl or immediate-release metoprolol including tinnitus ringing in ears .
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at steady state the average bioavailability of metoprolol following administration of toprol-xl, across the dosage range of 50 to 400 mg once daily, was 77 relative to the corresponding single or divided doses of conventional metoprolol.